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\u7d9a\u3051\u306a\u304d\u3083\u3044\u3051\u306a\u3044\u3067\u3059\u3088\u306d\u3002\u6b21\u4e16\u4ee3\u306e \u30ef\u30af\u30c1\u30f3\u3060\u3063\u305f\u308a\u3001\u65b0\u3057\u3044\u6cbb\u7642\u85ac\u3060\u3063\u305f\u308a \u3001\u305d\u3057\u3066\u672a\u6765\u306b\u307e\u305f\u6765\u308b\u304b\u3082\u3057\u308c\u306a\u3044 \u30d1\u30f3\u30c7\u30df\u30c3\u30af\u3078\u306e\u5099\u3048\u3060\u3063\u305f\u308a\u3002\u3053\u306e \u7d42\u308f\u3089\u306a\u3044\u7af6\u4e89\u306e\u4e2d\u3067\u50d5\u305f\u3061\u306f\u6b21\u306b\u3069\u3093\u306a \u4e00\u624b\u3092\u6253\u3064\u3079\u304d\u306a\u3093\u3067\u3057\u3087\u3046\u304b\u3002\u30af\u738b \u30a2\u30ab\u30c7\u30df\u30a2\u30c1\u30e3\u30f3\u30cd\u30eb\u767b\u9332\u3068\u3044\u3044\u306d\u3092 \u3088\u308d\u3057\u304f\u304a\u9858\u3044\u3057\u307e\u3059\u3002 <\/p>\n<p>\n\u5143\u306e\u8ad6\u6587<br \/>\nSARS-CoV-2 Variants: Biology, Pathogenicity, Immunity and Control<\/p>\n<p>Citation<br \/>\nUraki R, Korber B, Diamond MS, Kawaoka Y. Nat Rev Microbiol. 2025; published online Nov 2025. doi:10.1038\/s41579-025-01255-x.<\/p>\n<p>\u8981\u7d04<br \/>\n\u672c\u7dcf\u8aac\u306f\u3001SARS-CoV-2\u306e\u9032\u5316\u3001\u751f\u7269\u5b66\u7684\u7279\u6027\u3001\u75c5\u539f\u6027\u3001\u514d\u75ab\u9003\u907f\u3001\u305d\u3057\u3066\u30ef\u30af\u30c1\u30f3\u6226\u7565\u306e\u6700\u524d\u7dda\u3092\u5305\u62ec\u7684\u306b\u6574\u7406\u3057\u3066\u3044\u308b\u30022019\u5e74\u306e\u51fa\u73fe\u4ee5\u6765\u3001\u30a6\u30a4\u30eb\u30b9\u306f\u611f\u67d3\u6027\u3068\u514d\u75ab\u9003\u907f\u306e\u30d0\u30e9\u30f3\u30b9\u3092\u4fdd\u3061\u306a\u304c\u3089\u9032\u5316\u3057\u3001\u30a2\u30eb\u30d5\u30a1\u3001\u30c7\u30eb\u30bf\u3001\u30aa\u30df\u30af\u30ed\u30f3\u306a\u3069\u306e\u4e3b\u8981\u5909\u7570\u682a\u3092\u7d4c\u3066\u30012025\u5e74\u73fe\u5728\u306fJN.1\u7cfb\u7d71\u304b\u3089\u6d3e\u751f\u3057\u305fXFG\u3001NB.1.8.1\u306a\u3069\u304c\u4e3b\u6d41\u3068\u306a\u3063\u3066\u3044\u308b\u3002\u3053\u308c\u3089\u306e\u65b0\u7cfb\u7d71\u306fACE2\u7d50\u5408\u80fd\u3092\u9ad8\u3081\u3064\u3064\u514d\u75ab\u56de\u907f\u3092\u5f37\u5316\u3057\u3066\u304a\u308a\u3001\u7279\u306bL455S\/F456L\u5909\u7570\u304c\u9375\u3067\u3042\u308b\u3002\u30aa\u30df\u30af\u30ed\u30f3\u682a\u4ee5\u964d\u306fTMPRSS2\u4f9d\u5b58\u6027\u304c\u4f4e\u4e0b\u3057\u3001\u4e0a\u6c17\u9053\u611f\u67d3\u3078\u306e\u9069\u5fdc\u3068\u3068\u3082\u306b\u75c5\u539f\u6027\u306f\u4f4e\u4e0b\u3057\u305f\u304c\u3001\u611f\u67d3\u529b\u306f\u7dad\u6301\u3055\u308c\u305f\u3002\u81e8\u5e8a\u7684\u306b\u306f\u3001\u91cd\u75c7\u5316\u7387\u306f\u4f4e\u3044\u3082\u306e\u306e\u3001\u514d\u75ab\u4f4e\u4e0b\u8005\u3084\u9ad8\u9f62\u8005\u3067\u306f\u4f9d\u7136\u3068\u3057\u3066\u91cd\u7be4\u5316\u30ea\u30b9\u30af\u304c\u6b8b\u308b\u3002\u30ef\u30af\u30c1\u30f3\u306fJN.1\u307e\u305f\u306fKP.2\u682a\u3092\u6297\u539f\u3068\u3059\u308b\u5358\u4fa1\u578b\u304c\u63a8\u5968\u3055\u308c\u3001\u514d\u75ab\u5237\u308a\u8fbc\u307f\uff08original antigenic sin\uff09\u304c\u5909\u7570\u5bfe\u5fdc\u30ef\u30af\u30c1\u30f3\u306e\u52b9\u679c\u3092\u5236\u9650\u3059\u308b\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u305f\u3002\u4eca\u5f8c\u306f\u3001\u7d4c\u9f3b\u578b\u30ef\u30af\u30c1\u30f3\u3084T\u7d30\u80de\u514d\u75ab\u8a98\u5c0e\u578b\u30ef\u30af\u30c1\u30f3\u306e\u958b\u767a\u304c\u8ab2\u984c\u3067\u3042\u308a\u3001\u9577\u671f\u7684\u306b\u306f\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u3068\u540c\u69d8\u306b\u5b9a\u671f\u7684\u306a\u682a\u66f4\u65b0\u3068\u4e88\u6e2c\u30e2\u30c7\u30eb\u306b\u57fa\u3065\u304f\u6297\u539f\u9078\u5b9a\u304c\u5fc5\u8981\u3068\u3055\u308c\u308b\u3068\u7d50\u8ad6\u3065\u3051\u3066\u3044\u308b\u3002<\/p>\n<p>\u5927\u962a\u5927\u5b66\u5927\u5b66\u9662\u533b\u5b66\u7cfb\u7814\u7a76\u79d1 \u611f\u67d3\u5236\u5fa1\u5b66\u8b1b\u5ea7\u3067\u306f<\/p>\n<p>\u30fb\u611f\u67d3\u75c7\u5c02\u9580\u5bb6\u306e\u80b2\u6210<br \/>\n\u30fb\u611f\u67d3\u75c7\u7814\u7a76<br \/>\n\u30fb\u6b63\u3057\u3044\u611f\u67d3\u75c7\u60c5\u5831\u306e\u767a\u4fe1<br \/>\n\u30fb\u533b\u7642\u6a5f\u95a2\u3084\u9ad8\u9f62\u8005\u65bd\u8a2d\u306a\u3069\u3078\u306e\u611f\u67d3\u5bfe\u7b56\u652f\u63f4<\/p>\n<p>\u306e\u305f\u3081\u306b\u3054\u5bc4\u4ed8\u3092\u304a\u9858\u3044\u3057\u3066\u304a\u308a\u307e\u3059\u3002<br \/>\n\u3054\u5bc4\u4ed8\u306f\u4ee5\u4e0b\u306eHP\u3088\u308a\u304a\u7533\u3057\u8fbc\u307f\u3044\u305f\u3060\u3051\u307e\u3059\u3002<\/p>\n<p>https:\/\/www.med.osaka-u.ac.jp\/pub\/hp-infect\/donation<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u5909\u7570\u682a\u306f\u306a\u305c\u6b21\u3005\u3068\u73fe\u308c\u308b\u306e\u304b\uff1f \u30d1\u30f3\u30c7\u30df\u30c3\u30af\u304b\u3089\u6570\u5e74\u304c\u7d4c\u3061\u307e\u3057\u305f\u3051\u3069\u3001 \u79c1\u305f\u3061\u306e\u751f\u6d3b\u3092\u30ac\u3089\u308a\u3068\u5909\u3048\u305f\u65b0\u578b\u30b3\u30ed\u30ca 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