{"id":3312,"date":"2026-07-01T10:02:06","date_gmt":"2026-07-01T10:02:06","guid":{"rendered":"https:\/\/www.wacoca.com\/health\/3312\/"},"modified":"2026-07-01T10:02:06","modified_gmt":"2026-07-01T10:02:06","slug":"%e3%80%8c-%e8%83%9a%e7%9b%a4%e8%83%9e%e8%a3%9c%e5%ae%8c%e6%b3%95%e3%82%92%e7%94%a8%e3%81%84%e3%81%9f%e6%a9%9f%e8%83%bd%e7%9a%84%e3%81%aa%e5%89%af%e7%94%b2%e7%8a%b6%e8%85%ba%e5%86%8d%e7%94%9f-%e3%80%8d","status":"publish","type":"post","link":"https:\/\/www.wacoca.com\/health\/3312\/","title":{"rendered":"\u300c \u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u3092\u7528\u3044\u305f\u6a5f\u80fd\u7684\u306a\u526f\u7532\u72b6\u817a\u518d\u751f \u300d\u3010\u4e2d\u5185\u5553\u5149 \u7279\u5225\u6804\u8a89\u6559\u6388\u3011 | Science Tokyo \u65e7\u30fb\u6771\u4eac\u533b\u79d1\u6b6f\u79d1\u5927\u5b66"},"content":{"rendered":"
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\u6771\u4eac\u533b\u79d1\u6b6f\u79d1\u5927\u5b66\u306f\u30012024\u5e7410\u6708\u306b\u6771\u4eac\u5de5\u696d\u5927\u5b66\u3068\u7d71\u5408\u3057\u3001\u6771\u4eac\u79d1\u5b66\u5927\u5b66\uff08Science Tokyo\uff09\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u672c\u30b5\u30a4\u30c8\u306e\u60c5\u5831\u306f\u3001\u9806\u6b21\u3001Science Tokyo\u306e\u30b5\u30a4\u30c8<\/a>\u306b\u79fb\u884c\u3057\u3066\u3044\u304d\u307e\u3059\u3002\u516c\u958b\u3055\u308c\u3066\u3044\u308b\u30da\u30fc\u30b8\u306f\u6771\u4eac\u79d1\u5b66\u5927\u5b66\u306e\u60c5\u5831\u3068\u3057\u3066\u6709\u52b9\u306a\u3082\u306e\u3067\u3059\u3002<\/p>\n<\/div>\n


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\n\u56fd\u7acb\u5927\u5b66\u6cd5\u4eba\u7b51\u6ce2\u5927\u5b66

\n\u8056\u30de\u30ea\u30a2\u30f3\u30ca\u533b\u79d1\u5927\u5b66<\/p>\n<\/div>\n


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\n\u2015\u3000\u30ab\u30eb\u30b7\u30a6\u30e0\u5fdc\u7b54\u6027\u3092\u3082\u3064\u526f\u7532\u72b6\u817a\u3092\u52d5\u7269\u4f53\u5185\u3067\u69cb\u7bc9\u3000\u2015
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\u3000\u526f\u7532\u72b6\u817a\u306f\u7532\u72b6\u817a\u306e\u5468\u56f2\u306b\u5b58\u5728\u3059\u308b\u7c73\u7c92\u5927\u306e\u3068\u3066\u3082\u5c0f\u3055\u306a\u5185\u5206\u6ccc\u5668\u5b98\u3067\u3059\u3002\u81d3\u5668\u3068\u3057\u3066\u306e\u5927\u304d\u3055\u3068\u306f\u88cf\u8179\u306b\u305d\u306e\u6a5f\u80fd\u306f\u6975\u3081\u3066\u91cd\u8981\u3067\u3001\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u3092\u4ecb\u3057\u3066\u4f53\u5185\u306e\u30ab\u30eb\u30b7\u30a6\u30e0\u4ee3\u8b1d\u3092\u5236\u5fa1\u3057\u3066\u3044\u307e\u3059\u3002\u7532\u72b6\u817a\u3042\u308b\u3044\u306f\u9838\u90e8\u306e\u75c5\u6c17\u3067\u5fc5\u8981\u306a\u5916\u79d1\u624b\u8853\u3084\u653e\u5c04\u7dda\u6cbb\u7642\u306b\u3088\u308a\u3001\u526f\u7532\u72b6\u817a\u6a5f\u80fd\u304c\u969c\u5bb3\u3055\u308c\u308b\u3053\u3068\u3042\u308a\u307e\u3059\u3002\u526f\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u306b\u9665\u308b\u3068\u3001\u30d3\u30bf\u30df\u30f3\uff24\u88fd\u5264\u3084\u30ab\u30eb\u30b7\u30a6\u30e0\u88fd\u5264\u3092\u3001\u751f\u6daf\u306b\u308f\u305f\u308a\u6bce\u65e5\u6b20\u304b\u3055\u305a\u5185\u670d\u3057\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u526f\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u306b\u5bfe\u3059\u308b\u3053\u306e\u3088\u3046\u306a\u88dc\u5145\u7642\u6cd5\u306f\u3001\u8840\u4e2d\u30ab\u30eb\u30b7\u30a6\u30e0\u6fc3\u5ea6\u306b\u5fdc\u3058\u3066\u7d30\u304b\u304f\u5909\u52d5\u3059\u308b\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u3092\u5b8c\u5168\u306b\u306f\u518d\u73fe\u3067\u304d\u305a\u3001\u6642\u306b\u5f0a\u5bb3\u3092\u6765\u3059\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u526f\u7532\u72b6\u817a\u306e\u518d\u751f\u533b\u7642\u304c\u3001\u3053\u306e\u3088\u3046\u306a\u5f93\u6765\u6cbb\u7642\u306e\u554f\u984c\u70b9\u3092\u89e3\u6c7a\u3057\u3001\u3088\u308a\u751f\u7406\u7684\u304b\u3064\u5b89\u5168\u306a\u6cbb\u7642\u624b\u6bb5\u3068\u306a\u308a\u5f97\u308b\u3068\u8003\u3048\u307e\u3057\u305f\u3002

\n\u3000\u526f\u7532\u72b6\u817a\u3092\u518d\u751f\u3059\u308b\u305f\u3081\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u3057\u3066\u3001\u8a66\u9a13\u7ba1\u5185\u3067\u591a\u80fd\u6027\u5e79\u7d30\u80de\u304b\u3089\u526f\u7532\u72b6\u817a\u306e\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u7d30\u80de\u3078\u306e\u5206\u5316\u3092\u8a98\u5c0e\u3059\u308b\u65b9\u6cd5\u304c\u3042\u308a\u307e\u3059\u3002\u6d77\u5916\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u306f\u3001\u3053\u306e\u65b9\u6cd5\u3067\u526f\u7532\u72b6\u817a\u69d8\u7d30\u80de\u304c\u4f5c\u88fd\u3055\u308c\u305f\u3068\u3059\u308b\u7814\u7a76\u8ad6\u6587\u304c\u51fa\u3066\u3044\u307e\u3059\u304c\u3001\u30ab\u30eb\u30b7\u30a6\u30e0\u6fc3\u5ea6\u306b\u5fdc\u3058\u3066\u526f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u8abf\u7bc0\u304c\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u3084\u3001\u52d5\u7269\u4f53\u5185\u3067\u6a5f\u80fd\u3059\u308b\u304b\u3069\u3046\u304b\u306b\u3064\u3044\u3066\u306f\u672a\u3060\u691c\u8a3c\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u526f\u7532\u72b6\u817a\u306b\u9650\u3089\u305a\u3059\u3079\u3066\u306e\u5185\u5206\u6ccc\u81d3\u5668\u3067\u91cd\u8981\u306a\u3053\u3068\u306f\u3001\u30db\u30eb\u30e2\u30f3\u3092\u5206\u6ccc\u3059\u308b\u3053\u3068\u3001\u305d\u3057\u3066\u3001\u5468\u56f2\u306e\u74b0\u5883\u306b\u5fdc\u3058\u3066\u305d\u306e\u5206\u6ccc\u3092\u8abf\u7bc0\u3067\u304d\u308b\u3053\u3068\u3067\u3059\u3002

\n\u3000\u672c\u7814\u7a76\u3067\u306f\u3001\u8a66\u9a13\u7ba1\u5185\u3067\u306f\u306a\u304f\u3001\u52d5\u7269\u4f53\u5185\u3067\u81d3\u5668\u3092\u69cb\u7bc9\u3059\u308b\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u306e\u6280\u8853\u3092\u7528\u3044\u3066\u3001\u591a\u80fd\u6027\u5e79\u7d30\u80de\u7531\u6765\u306e\u6a5f\u80fd\u7684\u306a\u526f\u7532\u72b6\u817a\u3092\u4f5c\u88fd\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u307e\u3057\u305f\u3002<\/p>\n


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\n \u7814\u7a76\u6210\u679c\u306e\u6982\u8981 \n <\/p>\n


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\u3000\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u52d5\u7269\u306e\u767a\u751f\u904e\u7a0b\u3092\u5229\u7528\u3059\u308b\u81d3\u5668\u518d\u751f\u6cd5\u3067\u3042\u308b\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u306b\u3088\u308a\u3001\u526f\u7532\u72b6\u817a\u6b20\u640d\u30de\u30a6\u30b9\u4f53\u5185\u306b\u30de\u30a6\u30b9ES\u7d30\u80de\u7531\u6765\u306e\u526f\u7532\u72b6\u817a\u3092\u4f5c\u88fd\u3059\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f(\u56f3A)\u3002\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u306f\u3001\u907a\u4f1d\u7684\u306b\u81d3\u5668\u304c\u6b20\u640d\u3059\u308b\u52d5\u7269\u306e\u4f53\u5185\u3067\u3001\u591a\u80fd\u6027\u5e79\u7d30\u80de\u7531\u6765\u306e\u81d3\u5668\u3092\u4f5c\u88fd\u3059\u308b\u624b\u6cd5\u3067\u3059\u3002\u81d3\u5668\u6b20\u640d\u52d5\u7269\u306e\u7740\u5e8a\u524d\u80da\u306b\u30c9\u30ca\u30fc\u591a\u80fd\u6027\u5e79\u7d30\u80de\u3092\u6ce8\u5165\u3057\u3066\u304b\u3089\u4ee3\u7406\u6bcd\u306e\u5b50\u5bae\u306b\u79fb\u690d\u3059\u308b\u3068\u3001\u672c\u6765\u306f\u6b20\u640d\u3059\u308b\u81d3\u5668\u304c\u30c9\u30ca\u30fc\u7d30\u80de\u306b\u3088\u308a\u6b63\u5e38\u306b\u5f62\u6210\u3055\u308c\u305f\u30ad\u30e1\u30e9\u500b\u4f53\u304c\u751f\u307e\u308c\u307e\u3059\u3002\u3053\u306e\u624b\u6cd5\u3092\u3001\u9f67\u6b6f\u985e\uff08\u30de\u30a6\u30b9\u30fb\u30e9\u30c3\u30c8\uff09\u3084\u5927\u578b\u52d5\u7269\uff08\u30d6\u30bf\u306a\u3069\u306e\u5bb6\u755c\uff09\u306b\u9069\u5fdc\u3059\u308b\u3053\u3068\u3067\u3001\u30d2\u30c8\u306e\u7d30\u80de\u306e\u307f\u3067\u69cb\u6210\u3055\u308c\u305f\u79fb\u690d\u7528\u81d3\u5668\u3092\u5f97\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u60a3\u8005\u672c\u4eba\u306e\u591a\u80fd\u6027\u5e79\u7d30\u80de\u3092\u4f7f\u3046\u3053\u3068\u306b\u3088\u308a\u3001\u514d\u75ab\u6291\u5236\u5264\u3092\u4f7f\u308f\u306a\u304f\u3066\u3082\u62d2\u7d76\u3055\u308c\u306a\u3044\u81d3\u5668\u3082\u4f5c\u88fd\u53ef\u80fd\u3067\u3059\u3002

\n\u3000\u672c\u7814\u7a76\u3067\u306f\u3001\u30de\u30a6\u30b9\u30e2\u30c7\u30eb\u3092\u7528\u3044\u3066\u3001\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u306b\u3088\u308a\u6a5f\u80fd\u7684\u306a\u526f\u7532\u72b6\u817a\u3092\u4f5c\u88fd\u3067\u304d\u308b\u3053\u3068\u3092\u8a3c\u660e\u3057\u307e\u3057\u305f\u3002\u306f\u3058\u3081\u306b\u3001CRISPR-Cas9\u203b\uff13\u306b\u3088\u308b\u53d7\u7cbe\u5375\u30b2\u30ce\u30e0\u7de8\u96c6\u3092\u7528\u3044\u308b\u3053\u3068\u306b\u3088\u308a\u526f\u7532\u72b6\u817a\u6b20\u640d\u30de\u30a6\u30b9\u3092\u52b9\u7387\u7684\u306b\u4f5c\u88fd\u3057\u307e\u3057\u305f\u3002\u6a19\u7684\u3068\u3057\u305f\u907a\u4f1d\u5b50\u306fGcm2\u3068\u3044\u3046\u526f\u7532\u72b6\u817a\u767a\u751f\u306b\u5fc5\u9808\u306e\u907a\u4f1d\u5b50\u3067\u3001\u3053\u306e\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u3092\u5b8c\u5168\u306b\u6b20\u304f\u3068\u526f\u7532\u72b6\u817a\u304c\u3067\u304d\u306a\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u5f93\u6765\u306e\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u306b\u3088\u308a\u81d3\u5668\u3092\u4f5c\u88fd\u3059\u308b\u969b\u306f\u3001\u4e21\u89aa\u7531\u6765\u306e\u907a\u4f1d\u5b50\uff12\u672c\u306e\u5185\u3001\u7247\u65b9\u306e\u307f\u304c\u6a5f\u80fd\u7834\u58ca\u3055\u308c\u3066\u3044\u308b\u500b\u4f53\uff08\u30d8\u30c6\u30ed\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u500b\u4f53\uff09\u540c\u58eb\u3092\u4ea4\u914d\u3055\u305b\u308b\u3053\u3068\u3067\u3001\u4e21\u65b9\u306e\u907a\u4f1d\u5b50\u304c\u7834\u58ca\u3055\u308c\u305f\u53d7\u7cbe\u5375\uff08\u30db\u30e2\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u80da\uff09\u3092\u300125\uff05\u306e\u78ba\u7387\u3067\u5f97\u3066\u3044\u307e\u3057\u305f\u3002\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u91ce\u751f\u578b\u306e\u53d7\u7cbe\u5375\u306b\u5bfe\u3057\u3066Gcm2\u907a\u4f1d\u5b50\u306e\u6700\u91cd\u8981\u9818\u57df\u3092\u72d9\u3063\u305f\u30b2\u30ce\u30e0\u7de8\u96c6\u3092\u884c\u3046\u3053\u3068\u3067\u3001\u4ea4\u914d\u3092\u884c\u308f\u306a\u304f\u3066\u3082\u6975\u3081\u3066\u9ad8\u52b9\u7387\u306bGcm2\u907a\u4f1d\u5b50\u30db\u30e2\u6b20\u640d\u80da\uff08\u526f\u7532\u72b6\u817a\u6b20\u640d\u30de\u30a6\u30b9\u53d7\u7cbe\u5375\uff09\u3092\u5f97\u308b\u3053\u3068\u306b\u6210\u529f\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u52b9\u7387\u6027\u306e\u6539\u5584\u3060\u3051\u3067\u306a\u304f\u3001\u81d3\u5668\u4f5c\u88fd\u306b\u7528\u3044\u308b\u5b9f\u9a13\u52d5\u7269\u306e\u6570\u3092\u6e1b\u3089\u3059\u3053\u3068\u306b\u3082\u3064\u306a\u304c\u308a\u307e\u3059\u3002Gcm2\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30de\u30a6\u30b9\u306f\u526f\u7532\u72b6\u817a\u3092\u6b20\u304f\u3053\u3068\u3067\u526f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3092\u5206\u6ccc\u3067\u304d\u305a\u3001\u91cd\u5ea6\u306e\u4f4e\u30ab\u30eb\u30b7\u30a6\u30e0\u8840\u75c7\u306b\u9665\u308a\u3001\u751f\u5f8c\u76f4\u5f8c\u306b\u6b7b\u4ea1\u3057\u307e\u3059\u3002

\n\u3000\u6b21\u306b\u3001\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u3092\u7528\u3044\u3066\u3001\u3053\u306eGcm2\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30de\u30a6\u30b9\u53d7\u7cbe\u5375\u306b\u30de\u30a6\u30b9ES\u7d30\u80de\u3092\u6ce8\u5165\u3057\u3066\u30ad\u30e1\u30e9\u30de\u30a6\u30b9\u3092\u4f5c\u88fd\u3057\u307e\u3057\u305f\u3002\u591a\u304f\u306e\u30ad\u30e1\u30e9\u30de\u30a6\u30b9\u304c\u6b63\u5e38\u306b\u6210\u4f53\u307e\u3067\u767a\u80b2\u3057\u3001\u6b63\u5e38\u306a\u8840\u4e2d\u30ab\u30eb\u30b7\u30a6\u30e0\u6fc3\u5ea6\u3092\u793a\u3057\u3001\u4f4e\u30ab\u30eb\u30b7\u30a6\u30e0\u8840\u75c7\u7b49\u306b\u3088\u308b\u5408\u4f75\u75c7\u3092\u6765\u3059\u3053\u3068\u3082\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u30ad\u30e1\u30e9\u30de\u30a6\u30b9\u4f53\u5185\u306e\u526f\u7532\u72b6\u817a\u306f\u3001\u30de\u30a6\u30b9ES\u7d30\u80de\u7531\u6765\u306e\u7d30\u80de\u304b\u3089\u69cb\u7bc9\u3055\u308c\u3066\u304a\u308a\u3001\u526f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3092\u5e83\u304f\u767a\u73fe\u3057\u3066\u3044\u307e\u3057\u305f\uff08\u56f3B\uff09\u3002\u751f\u4f53\u304c\u4f4e\u30ab\u30eb\u30b7\u30a6\u30e0\u8840\u75c7\u306b\u6652\u3055\u308c\u305f\u6642\u306b\u526f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u304c\u901f\u3084\u304b\u306b\u5206\u6ccc\u3055\u308c\u3001\u4f4e\u30ab\u30eb\u30b7\u30a6\u30e0\u8840\u75c7\u3092\u6b63\u5e38\u3078\u3068\u662f\u6b63\u3059\u308b\u6a5f\u69cb\u306f\u751f\u547d\u7dad\u6301\u306b\u6975\u3081\u3066\u91cd\u8981\u3067\u3059\u3002\u305d\u3053\u3067\u3001\u30de\u30a6\u30b9ES\u7d30\u80de\u306b\u3088\u308a\u88dc\u5b8c\u3055\u308c\u305fGcm2\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30de\u30a6\u30b9\u306b\u5bfe\u3057\u3066\u3001\u70ad\u9178\u6c34\u7d20\u30a4\u30aa\u30f3\u306b\u3088\u308a\u4eba\u70ba\u7684\u306b\u4f4e\u30ab\u30eb\u30b7\u30a6\u30e0\u8840\u75c7\u3092\u60f9\u8d77\u3057\u305f\u3068\u3053\u308d\u3001\u901a\u5e38\u306e\u30de\u30a6\u30b9\u306e\u526f\u7532\u72b6\u817a\u3068\u540c\u7b49\u7a0b\u5ea6\u306b\u526f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3092\u5206\u6ccc\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u4ee5\u4e0a\u306e\u3053\u3068\u304b\u3089\u3001\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u3092\u7528\u3044\u3066Gcm2\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30de\u30a6\u30b9\u5185\u306b\u4f5c\u88fd\u3055\u308c\u305f\u30de\u30a6\u30b9ES\u7d30\u80de\u7531\u6765\u306e\u526f\u7532\u72b6\u817a\u306f\u3001\u2460\u526f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3092\u4ecb\u3057\u3066\u8840\u4e2d\u30ab\u30eb\u30b7\u30a6\u30e0\u6fc3\u5ea6\u3092\u6b63\u5e38\u306b\u7dad\u6301\u3059\u308b\u3001\u2461\u672b\u68a2\u306e\u4f4e\u30ab\u30eb\u30b7\u30a6\u30e0\u523a\u6fc0\u306b\u5fdc\u7b54\u3057\u3066\u526f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3092\u5206\u6ccc\u3059\u308b\u3001\u3068\u3044\u3046\uff12\u70b9\u3092\u6e80\u305f\u3057\u3001\u6210\u719f\u3057\u305f\u5185\u5206\u6ccc\u5668\u5b98\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002

\n\u3000\u6b21\u306b\u3001\u30de\u30a6\u30b9ES\u7d30\u80de\u7531\u6765\u306e\u526f\u7532\u72b6\u817a\u304c\u79fb\u690d\u81d3\u5668\u3068\u3057\u3066\u6a5f\u80fd\u3059\u308b\u304b\u3069\u3046\u304b\u3092\u691c\u8a3c\u3057\u307e\u3057\u305f\u3002\u81e8\u5e8a\u4e0a\u3001\u6700\u3082\u983b\u5ea6\u304c\u9ad8\u3044\u526f\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u306f\u3001\u5916\u79d1\u624b\u8853\u5f8c\u306b\u8d77\u3053\u308b\u3082\u306e\u3067\u3059\u3002\u305d\u3053\u3067\u3001\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u526f\u7532\u72b6\u817a\u3092\u5916\u79d1\u7684\u306b\u6458\u51fa\u3059\u308b\u3053\u3068\u3067\u526f\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u3092\u4f5c\u88fd\u3057\u3001\u305d\u308c\u3089\u306e\u30de\u30a6\u30b9\u306e\u814e\u88ab\u819c\u4e0b\u306b\u30de\u30a6\u30b9ES\u7d30\u80de\u7531\u6765\u306e\u526f\u7532\u72b6\u817a\u3092\u79fb\u690d\u3057\u307e\u3057\u305f\u3002\u814e\u88ab\u819c\u4e0b\u79fb\u690d\u5f8c\u3001\u8840\u4e2d\u30ab\u30eb\u30b7\u30a6\u30e0\u6fc3\u5ea6\u3084\u70ad\u9178\u6c34\u7d20\u30a4\u30aa\u30f3\u6295\u4e0e\u5f8c\u306e\u526f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u5024\u306b\u6709\u610f\u306a\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\uff08\u56f3C\uff09\u3002\u3053\u306e\u3053\u3068\u306f\u3001\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u3092\u7528\u3044\u3066Gcm2\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30de\u30a6\u30b9\u5185\u306b\u4f5c\u88fd\u3055\u308c\u305f\u30de\u30a6\u30b9ES\u7d30\u80de\u7531\u6765\u306e\u526f\u7532\u72b6\u817a\u304c\u79fb\u690d\u81d3\u5668\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001\u526f\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u306e\u75c5\u614b\u3092\u6539\u5584\u3055\u305b\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u6700\u5f8c\u306b\u3001\u7570\u7a2e\u9593\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u306b\u3088\u308aGcm2\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30e9\u30c3\u30c8\u4f53\u5185\u3067\u7570\u7a2e\u3067\u3042\u308b\u30de\u30a6\u30b9ES\u7d30\u80de\u7531\u6765\u306e\u526f\u7532\u72b6\u817a\u4f5c\u88fd\u3092\u8a66\u307f\u307e\u3057\u305f\u3002\u30e9\u30c3\u30c8\u4f53\u5185\u3067\u4f5c\u88fd\u3055\u308c\u305f\u30de\u30a6\u30b9ES\u7d30\u80de\u7531\u6765\u306e\u526f\u7532\u72b6\u817a\u306f\u3001\u907a\u4f1d\u5b50\u767a\u73fe\u89e3\u6790\u306b\u3088\u308a\u3001\u6210\u719f\u3057\u305f\u7d44\u7e54\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n


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\n \u7814\u7a76\u6210\u679c\u306e\u610f\u7fa9 \n <\/p>\n


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\u3000\u53d7\u7cbe\u5375\u30b2\u30ce\u30e0\u7de8\u96c6\u306b\u3088\u308b\u52b9\u7387\u7684\u306a\u81d3\u5668\u6b20\u640d\u80da\u306e\u4f5c\u88fd\u3068\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u3068\u3092\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u304c\u3001\u81d3\u5668\u88dc\u5b8c\u306e\u6709\u7528\u306a\u624b\u6bb5\u3068\u306a\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002\u3055\u3089\u306a\u308b\u6539\u826f\u306f\u5fc5\u8981\u3067\u3042\u308b\u3082\u306e\u306e\u3001\u7570\u7a2e\u9593\u3067\u306e\u526f\u7532\u72b6\u817a\u4f5c\u88fd\u304c\u53ef\u80fd\u3067\u3042\u308b\u3068\u3044\u3046\u672c\u7814\u7a76\u7d50\u679c\u306f\u3001\u5c06\u6765\u306e\u30d2\u30c8-\u52d5\u7269\u9593\u80da\u76e4\u80de\u88dc\u5b8c\u6cd5\u306b\u3088\u308b\u5185\u5206\u6ccc\u81d3\u5668\u4f5c\u88fd\u306e\u53ef\u80fd\u6027\u3092\u793a\u3059\u3082\u306e\u3067\u3042\u308a\u3001\u6a5f\u80fd\u7684\u306a\u5185\u5206\u6ccc\u81d3\u5668\u306e\u518d\u751f\u304a\u3088\u3073\u518d\u751f\u81d3\u5668\u306e\u79fb\u690d\u6cbb\u7642\u306b\u8ca2\u732e\u3059\u308b\u3082\u306e\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n


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\n \u7814\u7a76\u652f\u63f4 \n <\/p>\n


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\u3000\u672c\u7814\u7a76\u306f\u65e5\u672c\u533b\u7642\u7814\u7a76\u958b\u767a\u6a5f\u69cb \u518d\u751f\u533b\u7642\u5b9f\u73fe\u62e0\u70b9\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u30d7\u30ed\u30b0\u30e9\u30e0 \u75be\u60a3\u30fb\u7d44\u7e54\u5225\u5b9f\u7528\u5316\u7814\u7a76\u62e0\u70b9\uff08\u62e0\u70b9C\uff09\u300c\u52d5\u7269\u751f\u4f53\u5185\u74b0\u5883\u3092\u5229\u7528\u3057\u305f\u79fb\u690d\u7528\u30d2\u30c8\u81d3\u5668\u306e\u958b\u767a\u300d\uff08JP22bm1004002h\u3001\u7814\u7a76\u4ee3\u8868\u8005\uff1a\u4e2d\u5185\u5553\u5149\uff09\u3001\u540c\u9769\u65b0\u7684\u5148\u7aef\u7814\u7a76\u958b\u767a\u652f\u63f4\u4e8b\u696d\u30a4\u30f3\u30ad\u30e5\u30d9\u30fc\u30c8\u30bf\u30a4\u30d7(LEAP) \u300c\u767a\u751f\u539f\u7406\u306b\u57fa\u3065\u304f\u6a5f\u80fd\u7684\u7acb\u4f53\u81d3\u5668\u518d\u751f\u6280\u8853\u306e\u958b\u767a\u300d(JP19gm0010002\u3001\u7814\u7a76\u4ee3\u8868\u8005\uff1a\u4e2d\u5185\u5553\u5149)\u3001\u65e5\u672c\u5b66\u8853\u632f\u8208\u4f1a\uff08JSPS\uff09\u79d1\u5b66\u7814\u7a76\u8cbb\u52a9\u6210\u4e8b\u696d\u57fa\u76e4\u7814\u7a76B\uff08JP20H03638\u3001\u7814\u7a76\u4ee3\u8868\u8005\uff1a\u6c34\u8c37\u82f1\u4e8c\uff09\u304a\u3088\u3073\u540c\u82e5\u624b\u7814\u7a76\uff08JP21K16337\u3001\u7814\u7a76\u4ee3\u8868\u8005\uff1a\u52a0\u7d0d\u9ebb\u5f13\u5b50\uff09\u306b\u3088\u308b\u52a9\u6210\u3092\u53d7\u3051\u3066\u884c\u308f\u308c\u307e\u3057\u305f\u3002<\/p>\n


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\n \u7528\u8a9e\u89e3\u8aac \n <\/p>\n


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\u203b\uff11\u591a\u80fd\u6027\u5e79\u7d30\u80de\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u80ce\u76e4\u306a\u3069\u306e\u7d44\u7e54\uff08\u80da\u4f53\u5916\u7d44\u7e54\uff09\u3092\u9664\u304f\u4f53\u4e2d\u306e\u3055\u307e\u3056\u307e\u306a\u7d44\u7e54\u306b\u5206\u5316\u3059\u308b\u80fd\u529b\u3092\u3082\u3064\u7d30\u80de\u3002\u591a\u80fd\u6027\u5e79\u7d30\u80de\u306b\u306f\uff12\u7a2e\u985e\u3042\u308a\u3001\u53d7\u7cbe\u5375\u306b\u542b\u307e\u308c\u308b\u7d30\u80de\u3092\u57f9\u990a\u3057\u305f\u7d30\u80de\u306f\u300c\u80da\u6027\u5e79\u7d30\u80de\uff08ES\u7d30\u80de\uff09\u300d\u3001\u4f53\u7d30\u80de\u306b\u907a\u4f1d\u5b50\u3092\u5c0e\u5165\u3057\u3066\u4eba\u5de5\u7684\u306b\u6a39\u7acb\u3057\u305f\u7d30\u80de\u3092\u300c\u4eba\u5de5\u591a\u80fd\u6027\u5e79\u7d30\u80de\uff08iPS\u7d30\u80de\uff09\u300d\u3068\u3044\u3046\u3002<\/p>\n

\u203b\uff12\u30ad\u30e1\u30e9\u52d5\u7269\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30ad\u30e1\u30e9\u52d5\u7269\u3068\u306f\u3001\uff12\u3064\u4ee5\u4e0a\u306e\u907a\u4f1d\u7684\u80cc\u666f\u306e\u7570\u306a\u308b\u7d30\u80de\u306b\u3088\u3063\u3066\u69cb\u6210\u3055\u308c\u305f\uff11\u3064\u306e\u751f\u7269\u3067\u3042\u308a\u3001\uff11\u3064\u306e\u53d7\u7cbe\u5375\u304b\u3089\u7570\u306a\u308b\u907a\u4f1d\u5f62\u8cea\u3092\u3082\u3063\u305f\u7d30\u80de\u304c\u51fa\u73fe\u3059\u308b\u30e2\u30b6\u30a4\u30af\u3084\u3001\u7570\u306a\u308b\u907a\u4f1d\u5f62\u8cea\u3092\u3082\u3064\u52d5\u7269\u540c\u58eb\u306e\u4ea4\u914d\u3067\u3067\u304d\u308b\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u3068\u306f\u7570\u306a\u308b\u3002\u30ad\u30e1\u30e9\u52d5\u7269\u306f\u3001\u80da\u3068\u80da\u306e\u878d\u5408\u3001\u80da\u3078\u306e\u591a\u80fd\u6027\u5e79\u7d30\u80de\u306e\u6ce8\u5165\u306b\u3088\u3063\u3066\u4f5c\u88fd\u3067\u304d\u308b\u3002<\/p>\n

\u203b\uff13\u3000CRISPR-Cas9\u306b\u3088\u308b\u30b2\u30ce\u30e0\u7de8\u96c6\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u30fb\u539f\u6838\u751f\u7269\u306e\u6709\u3059\u308b\u7372\u5f97\u514d\u75ab\u6a5f\u69cb\u3067\u3042\u308bCRISPR\/Cas9\u30b7\u30b9\u30c6\u30e0\u3092\u3082\u3068\u306b\u958b\u767a\u3055\u308c\u305f\u907a\u4f1d\u5b50\u6539\u5909\u6280\u8853\u3002 \u30ac\u30a4\u30c9RNA(gRNA)\u3068\u3044\u3046\u6a19\u7684\u3092\u6307\u5b9a\u3059\u308bRNA\u3068\u3001\u4e8c\u672c\u9396DNA\u5207\u65ad\u6d3b\u6027\u3092\u6709\u3059\u308b Cas9 \u30bf\u30f3\u30d1\u30af\u3092\u7d30\u80de\u5185\u306b\u5c0e\u5165\u3059\u308b\u3068\u3001\u6838\u306b\u79fb\u884c\u3057\u305f\u5f8c\u3001gRNA\u3068\u76f8\u88dc\u7684\u306a\u30b2\u30ce\u30e0\u304c\u7279\u7570\u7684\u306b\u5207\u65ad\u3055\u308c\u308b\u3002\u5207\u65ad\u3055\u308c\u305f\u30b2\u30ce\u30e0DNA \u306f\u7d30\u80de\u304c\u5143\u3005\u3082\u3063\u3066\u3044\u308b\u30b2\u30ce\u30e0\u4fee\u5fa9\u6a5f\u69cb\u3067\u3064\u306a\u304e\u306a\u304a\u3055\u308c\u308b\u304c\u3001\u3053\u306e\u969b\u306b\u5fae\u5c0f\u306a\u30a8\u30e9\u30fc\u304c\u751f\u3058\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u3053\u308c\u3092\u5229\u7528\u3057\u3066gRNA\u304c\u6a19\u7684\u3068\u3059\u308b\u30b2\u30ce\u30e0\u90e8\u4f4d\u306e\u6a5f\u80fd\u3092\u6b20\u640d\u3055\u305b\u308b\u3002<\/p>\n<\/div>\n


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\n \u8ad6\u6587\u60c5\u5831 \n <\/p>\n


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\n

\u63b2\u8f09\u8a8c\uff1aProceedings of the National Academy of Sciences of the United States of America \uff08PNAS\uff09<\/p>\n

\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb\uff1aFunctional calcium-responsive parathyroid glands generated using single-step blastocyst complementation<\/p>\n

DOI\uff1ahttps:\/\/doi.org\/10.1073\/pnas.2216564120<\/a><\/p>\n<\/div>\n


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\n \u7814\u7a76\u8005\u30d7\u30ed\u30d5\u30a3\u30fc\u30eb \n <\/p>\n


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\u52a0\u7d0d\u3000\u9ebb\u5f13\u5b50\u3000\uff08\u30ab\u30ce\u30a6\u3000\u30de\u30e6\u30b3\uff09\u3000Kano Mayuko

\n\u8056\u30de\u30ea\u30a2\u30f3\u30ca\u533b\u79d1\u5927\u5b66\u3000\u4ee3\u8b1d\u30fb\u5185\u5206\u6ccc\u5185\u79d1\u5b66\u3000\u52a9\u6559

\n\u6771\u4eac\u533b\u79d1\u6b6f\u79d1\u5927\u5b66 \u9ad8\u7b49\u7814\u7a76\u9662 \u5353\u8d8a\u7814\u7a76\u90e8\u9580\u00a0

\n\u5e79\u7d30\u80de\u6cbb\u7642\u7814\u7a76\u5ba4\u3000\u9023\u643a\u7814\u7a76\u54e1

\n\u00a0\u30fb\u7814\u7a76\u9818\u57df

\n\u518d\u751f\u533b\u7642

\n\u4ee3\u8b1d\u30fb\u5185\u5206\u6ccc\u5b66<\/p>\n

\u6c34\u8c37\u3000\u82f1\u4e8c\uff08\u30df\u30ba\u30bf\u30cb\u3000\u30a8\u30a4\u30b8\uff09\u3000Mizutani Eiji

\n\u7b51\u6ce2\u5927\u5b66\u533b\u5b66\u533b\u7642\u7cfb\u3000\u5e79\u7d30\u80de\u6cbb\u7642\u7814\u7a76\u5ba4\u3000\u51c6\u6559\u6388

\n\u6771\u4eac\u533b\u79d1\u6b6f\u79d1\u5927\u5b66 \u9ad8\u7b49\u7814\u7a76\u9662 \u5353\u8d8a\u7814\u7a76\u90e8\u9580\u00a0

\n\u5e79\u7d30\u80de\u6cbb\u7642\u7814\u7a76\u5ba4\u3000\u9023\u643a\u7814\u7a76\u54e1

\n\u00a0\u30fb\u7814\u7a76\u9818\u57df

\n\u518d\u751f\u533b\u7642

\n\u767a\u751f\u5de5\u5b66<\/p>\n

\u4e2d\u5185\u3000\u5553\u5149\uff08\u30ca\u30ab\u30a6\u30c1\u3000\u30d2\u30ed\u30df\u30c4\uff09\u3000Nakauchi Hiromitsu

\n\u6771\u4eac\u533b\u79d1\u6b6f\u79d1\u5927\u5b66 \u9ad8\u7b49\u7814\u7a76\u9662 \u5353\u8d8a\u7814\u7a76\u90e8\u9580\u00a0

\n\u5e79\u7d30\u80de\u6cbb\u7642\u7814\u7a76\u5ba4\u3000\u7279\u5225\u6804\u8a89\u6559\u6388

\n\u30fb\u7814\u7a76\u9818\u57df

\n\u518d\u751f\u533b\u7642

\n\u5e79\u7d30\u80de\u751f\u7269\u5b66<\/p>\n<\/div>\n


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\n \u554f\u3044\u5408\u308f\u305b\u5148 \n <\/p>\n


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\n

\uff1c\u7814\u7a76\u306b\u95a2\u3059\u308b\u3053\u3068\uff1e

\n\u8056\u30de\u30ea\u30a2\u30f3\u30ca\u533b\u79d1\u5927\u5b66

\n\u4ee3\u8b1d\u30fb\u5185\u5206\u6ccc\u5185\u79d1\u5b66\u3000\u52a0\u7d0d\u3000\u9ebb\u5f13\u5b50\uff08\u30ab\u30ce\u30a6\u3000\u30de\u30e6\u30b3\uff09

\nE-mail\uff1akano[@]marianna-u.ac.jp<\/p>\n

\u7b51\u6ce2\u5927\u5b66\u533b\u5b66\u533b\u7642\u7cfb

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\nE-mail\uff1aemizutani[@]md.tsukuba.ac.jp<\/p>\n

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\u203bE-mail\u306f\u4e0a\u8a18\u30a2\u30c9\u30ec\u30b9[@]\u306e\u90e8\u5206\u3092@\u306b\u5909\u3048\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div>\n


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