{"id":2811,"date":"2026-06-29T21:56:57","date_gmt":"2026-06-29T21:56:57","guid":{"rendered":"https:\/\/www.wacoca.com\/health\/2811\/"},"modified":"2026-06-29T21:56:57","modified_gmt":"2026-06-29T21:56:57","slug":"hif-ph%e9%98%bb%e5%ae%b3%e8%96%ac%e3%83%ad%e3%82%ad%e3%82%b5%e3%83%87%e3%83%a5%e3%82%b9%e3%82%bf%e3%83%83%e3%83%88%e3%81%8c%e7%94%b2%e7%8a%b6%e8%85%ba%e3%83%9b%e3%83%ab%e3%83%a2%e3%83%b3%e6%a4%9c","status":"publish","type":"post","link":"https:\/\/www.wacoca.com\/health\/2811\/","title":{"rendered":"HIF-PH\u963b\u5bb3\u85ac\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u304c\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u691c\u67fb\u5024\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u3092\u30ea\u30a2\u30eb\u30ef\u30fc\u30eb\u30c9\u30c7\u30fc\u30bf\u3067\u767a\u898b | \u7814\u7a76\u30fb\u63a1\u629e\u60c5\u5831 | \u5c90\u961c\u5927\u5b66"},"content":{"rendered":"
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\u3000\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u306f\u305d\u306e\u5316\u5b66\u69cb\u9020\u4e0a\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3067\u3042\u308bT3(\u30c8\u30ea\u30e8\u30fc\u30c9\u30b5\u30a4\u30ed\u30cb\u30f3) (\uff0a4)\u69d8\u306e\u9aa8\u683c\u3092\u3082\u3064\u3053\u3068\u304b\u3089\u3001TSH\u3092\u6291\u5236\u3057\u3001T3,T4\u3092\u4f4e\u4e0b\u3055\u305b\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3057\u305f\u3002\u4e00\u65b9\u3067\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u5024\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u5834\u5408\u3067\u3082\u3001\u7532\u72b6\u817a\u6a5f\u80fd\u4f4e\u4e0b\u75c7\u69d8\u306e\u691c\u67fb\u30c7\u30fc\u30bf(\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u3084CK\u306e\u4e0a\u6607\u306a\u3069)\u306f\u8a8d\u3081\u3089\u308c\u305a\u3001\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u304c\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u69d8\u4f5c\u7528\u3092\u6301\u3064\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002
\u3000\u305d\u306e\u305f\u3081\u3001\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u3092\u4f7f\u7528\u4e2d\u306e\u60a3\u8005\u306b\u304a\u3051\u308b\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u691c\u67fb\u5024\u306e\u5224\u65ad\u306b\u3064\u3044\u3066\u306f\u5341\u5206\u306a\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3059\u3002
\u3000\u672c\u7814\u7a76\u6210\u679c\u306f\u30012023\u5e748\u670819\u65e5\u306b\u7c73\u56fd\u5185\u5206\u6ccc\u5b66\u4f1a\u306e\u6a5f\u95a2\u8a8c\u300cJournal of Clinical Endocrinology & Metabolism\u300d\u3067\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002\n<\/p>\n

\n\"20230915.png\"<\/a><\/div>\n

\u767a\u8868\u306e\u30dd\u30a4\u30f3\u30c8<\/p>\n

\u814e\u6027\u8ca7\u8840\u6cbb\u7642\u306e\u305f\u3081\u306e\u65b0\u85ac\u3067\u3042\u308bHIF-PH\u963b\u5bb3\u85ac\u306e\u4e2d\u3067\u3001\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u306f\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u3068\u4f3c\u305f\u9aa8\u683c\u3092\u3082\u3061\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u69d8\u306e\u4f5c\u7528\u3092\u3057\u5f97\u308b\u3053\u3068\u304c\u57fa\u790e\u7814\u7a76\u3067\u306f\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002
\n\u672c\u7814\u7a76\u3067\u306f\u3001\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u3001\u53ca\u3073\u4ed6\u306eHIF-PH\u963b\u5bb3\u85ac\u3067\u3042\u308b\u30c0\u30d7\u30ed\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u3092\u4f7f\u7528\u3057\u3066\u3044\u305f\u60a3\u8005\u306e\u30ab\u30eb\u30c6\u30c7\u30fc\u30bf\u3092\u7528\u3044\u3066\u3001\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u306e\u307f\u304c\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u691c\u67fb\u5024\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\uff08TSH\u30fb\u904a\u96e2T4\u306e\u6e1b\u5c11\uff09\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002
\n\u30ea\u30a2\u30eb\u30ef\u30fc\u30eb\u30c9\u30c7\u30fc\u30bf\u3067\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u304c\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u69d8\u4f5c\u7528\u3092\u6301\u3064\u53ef\u80fd\u6027\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n

\u8a73\u3057\u3044\u7814\u7a76\u5185\u5bb9\u306b\u3064\u3044\u3066<\/p>\n

HIF-PH\u963b\u5bb3\u85ac\u30ed\u30ad\u30b5\u30c7\u30e5\u30b9\u30bf\u30c3\u30c8\u304c\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u691c\u67fb\u5024\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u3092\u30ea\u30a2\u30eb\u30ef\u30fc\u30eb\u30c9\u30c7\u30fc\u30bf\u3067\u767a\u898b
<\/a><\/p>\n

\u8ad6\u6587\u60c5\u5831<\/p>\n

\u96d1\u8a8c\u540d\uff1aJournal of Clinical Endocrinology & Metabolism
\n\u8ad6\u6587\u540d\uff1aEffect of Roxadustat on Thyroid Function in Patients with Renal Anemia<\/p>\n

\u8457\u3000\u8005\uff1aTakuya Haraguchi, Yoshiyuki Hamamoto, Hitoshi Kuwata, Yuji Yamazaki, Susumu Nakatani, Takanori Hyo, Yuichiro Yamada, Daisuke Yabe, and Yutaka Seino
\nDOI\u756a\u53f7\uff1a 10.1210\/clinem\/dgad483<\/a>\u3000<\/p>\n

\u7528\u8a9e\u89e3\u8aac<\/p>\n

\uff0a\uff11\u3000HIF-PH(hypoxia-inducible factor-prolyl hydroxylase)\u963b\u5bb3\u85ac\uff1a
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\n\uff0a2\u3000TSH(thyroid stimulating hormone)\uff1a\u7532\u72b6\u817a\u523a\u6fc0\u30db\u30eb\u30e2\u30f3\uff1a
\u7532\u72b6\u817a\u306e\u6d3b\u52d5\u3092\u523a\u6fc0\u3057\u3001\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u5206\u6ccc\u3092\u8abf\u6574\u3059\u308b\u3002
\n\uff0a3\u3000T4(thyroxine)\uff1a\u30b5\u30a4\u30ed\u30ad\u30b7\u30f3\uff1a
\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u4e00\u7a2e\u3067\u3001T3\u306e\u524d\u99c6\u4f53\u3068\u306a\u308b\u7269\u8cea\u3002
\n\uff0a4\u3000T3(triiodothyronine)\uff1a\u30c8\u30ea\u30e8\u30fc\u30c9\u30b5\u30a4\u30ed\u30cb\u30f3\uff1a
\u7532\u72b6\u817a\u30db\u30eb\u30e2\u30f3\u306e\u4e00\u7a2e\u3067\u3001\u4f53\u5185\u306e\u4ee3\u8b1d\u3092\u8abf\u6574\u3059\u308b\u50cd\u304d\u304c\u3042\u308b\u3002 <\/p><\/div>\n","protected":false},"excerpt":{"rendered":"

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